Ann McDermott is the Esther Breslow Professor of Biological Chemistry at Columbia University. She studies the structure, flexibility and function of proteins using magnetic resonance methods. For example, her group studies the structure function and allosteric regulation of potassium ion channels, which play crucial roles in diverse contexts, from bacteria to the human nervous system. She has studied the structures and dynamics of amyloids whose formation is a critical step in cellular signaling in humans. On the basis of this research, she is the recipient of the Pure Award in Chemistry, the Eastern Analytic Symposium Award for Achievement in Magnetic Resonance, the Gunther Laukien award in NMR, and she is an elected member of both the American Academy of Arts and Sciences, and the National Academy of Sciences. She is a member of the board of trustees for Harvey Mudd College and the Board of the New York Structural Biology Center. Her research group has been supported by the National Institutes of Health, the National Science Foundation, the Department of Energy, the Sloan Research Foundation and the Cottrell Research Foundation. She has a B. Sc. from Harvey Mudd College, and a Ph. D. from the College of Chemistry at U. C. Berkeley, where she worked with Kenneth Sauer and Melvin Klein, and postgraduate training at MIT and the Francis Bitter National Magnet Laboratory with Robert Griffin.